Rudolf Cardinal - PhD thesis

PhD thesis

https://rcardinal.ddns.net/publications/2001/PhD

Cardinal RN (2001). Neuropsychology of reinforcement processes in the rat. Unpublished PhD thesis, University of Cambridge.

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Abstract	HTML	PDF	-
Title page; Contents; Preface; Abstract; Acknowledgements; Publications; Abbreviations. (Pages 1-18.)	PDF, 103 kb	PDF, 106 kb	-
Chapter 1, Introduction. Reviews psychological mechanisms for action in the rat, including those contributing to Pavlovian and instrumental conditioning; conditioned reinforcement; the neural basis of these processes; delayed reinforcement; impulsive choice and ways of studying it; what is known of the neural mechanisms mediating delayed reinforcement. (Pages 19-62.)	PDF, 729 kb	PDF, 2.0 Mb	a) Neuroscience and Biobehavioral Reviews [9] b) Progress in Brain Research [2] c) The Amygdala (book chapter) [1] d) Trends in Cognitive Science [4] e) Annals NYAS [13] f) International Congress Series [15]
Chapter 2, General methods. Subjects, surgery, histology, reinforcement schedules, apparatus, data analysis. (Pages 63-69.)	PDF, 610 kb	PDF, 2.3 Mb	-
Chapter 3, Role of the anterior cingulate cortex in the control over behaviour by Pavlovian conditioned stimuli. The effect of ACC lesions on temporally discriminated approach, responding for conditioned reinforcement with intra-accumbens amphetamine, autoshaping (acquisition), sucrose consumption, locomotor activity, discrete fear conditioning, autoshaping (performance), Pavlovian–instrumental transfer, and a two-stimulus temporally discriminated approach task. Discussion of ACC function in rodents and primates. (Pages 70-127.)	PDF, 2.7 Mb	PDF, 12.7 Mb	a) Behavioral Neuroscience (autoshaping performance) [8] b) Behavioral Neuroscience (the rest) [14]
Chapter 4, Role of the nucleus accumbens core and shell in Pavlovian–instrumental transfer. The effects of AcbC and AcbSh lesions on a response-specific PIT task. (Pages 128-147.)	PDF, 1.2 Mb	PDF, 20.9 Mb	Published in abstract and poster form only [iii]
Chapter 5, Local analysis of behaviour in the adjusting-delay task for assessing choice of delayed reinforcement. Cross-correlation of choice behaviour with the delay to reinforcement in the adjusting-delay task; computer simulations of alternative decision rules. (Pages 148-169.)	PDF, 608 kb	PDF, 610 kb	Neural Networks [10]
Chapter 6, The effects of d-amphetamine, chlordiazepoxide, alpha-flupenthixol and behavioural manipulations on choice of signalled and unsignalled delayed reinforcement. Acquisition of a delayed-reinforcement choice task in the presence and absence of signals during the delay to reinforcement; effects of amphetamine, chlordiazepoxide and alpha-flupenthixol on performance; effects of delay omission, cue manipulations, prefeeding, reversal of the order of delays, and extinction. (Pages 170-194.)	PDF, 349 kb	PDF, 393 kb	Psychopharmacology [3]
Chapter 7, Contributions of limbic and prefrontal circuitry to choice of delayed reinforcement. Effects of ACC, mPFC and AcbC lesions on a delayed-reinforcement choice task; effects of intra-Acb amphetamine. (Pages 195-234.)	PDF, 1.8 Mb	PDF, 6.8 Mb	Science [5]
Chapter 8, General discussion. Summary of results; further discussion of implications for ACC function; theories of learning and choice with delayed reward; theories of nucleus accumbens function; views of reinforcement learning; conclusion. (Pages 235-249.)	PDF, 301 kb	PDF, 392 kb	a) Choice, Behavioral Economics and Addiction (book chapter) [12] b) Annals NYAS [17]
References. (Pages 250-276.)	PDF, 283 kb	PDF, 285 kb	-
WHOLE THESIS (comprising all the above)	PDF, 8.6 Mb	PDF, 46.3 Mb	-

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